Blog
Latest updates and evidence-informed perspectives on bone healing.
Sonication is no longer about sensitivity but about reproducibility
Sonication has established diagnostic value in implant-associated infection, but variation in processing limits comparability across centres.
What AI changes in infection decisions
AI can shift what becomes visible in infection care, but it also shifts exposure, justification pressure, and failure modes.
Culture-negative fracture-related infection is not primarily a laboratory failure
A proportion of fracture-related infections remain culture-negative despite appropriate sampling, reflecting biological and spatial constraints rather than laboratory error.
Why is gentamicin still used locally in orthopaedics?
Gentamicin became embedded in local antibiotic delivery because it fit PMMA cement well, and practice consolidated before comparative evidence matured.
Long-term quality-of-life impact of fracture-related infection
Fracture-related infection affects long-term function and quality of life beyond infection control and radiographic healing.
Fragmented data in bone infection outcomes
Outcome data for bone infection remain fragmented, limiting reliable estimates of survival, burden, and long-term impact.
Chronic osteomyelitis is not just prolonged inflammation
Chronic osteomyelitis shows inflammatory activity, but immune coordination differs from acute infection.