Blog
Articles on bone healing, bone infection and orthopaedic materials.
Bone void fillers in tibial plateau fractures
Current evidence on bone void fillers in tibial plateau fractures, with focus on structural support, healing, and study limits.
Immune regulation in chronic osteomyelitis
Chronic osteomyelitis shows inflammatory activity, but immune regulation differs from the acute response.
Long-term quality-of-life impact of fracture-related infection
Fracture-related infection affects long-term function and quality of life beyond infection control and radiographic healing.
Gentamicin in local antibiotic delivery: how PMMA shaped current practice
Gentamicin became widely used for local antibiotic delivery because it could be incorporated into PMMA cement and used reproducibly in surgery.
Debridement in bone infection: the limits of antibiotic treatment
Antibiotics cannot remove necrotic bone or residual dead space, making debridement a critical component of infection control.
Interpreting Positive Cutibacterium acnes Cultures in PJI
How low-grade presentation, joint context, and species context shape interpretation of positive Cutibacterium findings in PJI.
Local antimicrobial strategies in orthopaedic infection
Local antimicrobial strategies in orthopaedic infection address different operative problems, ranging from wound prophylaxis to implant-surface protection.
How Bone Grafts and Biomaterials Change Over Time After Implantation
Different bone grafts and biomaterials used to fill, support, or reconstruct bone defects follow different time paths after implantation, from rapid loss to prolonged persistence or structural retention.
Visible Graft on Follow-up Imaging: What It Can Mean
A visible graft or graft substitute on follow-up imaging can be expected, misleading, reassuring, or concerning, depending on the material and the pattern over time.
What CoNS Means in Fracture-Related Infection
CoNS is a laboratory grouping whose meaning in fracture-related infection depends on sampling pattern, species resolution, and clinical context.
Sonication is no longer about sensitivity but about reproducibility
Sonication has established diagnostic value in implant-associated infection, but variation in processing limits comparability across centres.
What AI changes in infection decisions
AI can shift what becomes visible in infection care, but it also shifts exposure, justification pressure, and failure modes.
Culture-negative fracture-related infection is not primarily a laboratory failure
A proportion of fracture-related infections remain culture-negative despite appropriate sampling, reflecting biological and spatial constraints rather than laboratory error.
Fragmented data in bone infection outcomes
Outcome data for bone infection remain fragmented, limiting reliable estimates of survival, burden, and long-term impact.